Who will lead the New York underworld? Will the Green Goblin go good or give grief? What secret is Mary Jane keeping? And who is the mysterious new Spider-Man? There are plenty of questions to answer as the adventures of May "Mayday" Parker continue! As a vicious gang war heats up, Spider-Girl struggles to keep order - but when a longtime foe is killed in the crossfire, May finds herself targeted by his family! Can the newest New Warriors help Spider-Girl win the war and survive two vengeance-crazed villains? Wall-crawling gets crowded when a new Scarlet Spider swings into action - and Peter Parker mulls a return to the webs! But even with her dad as backup, can May defeat Apox the Omega Skrull? Plus, startling secrets of Mayday's past are revealed! Guest-starring the Fantastic Five!